Peptide Synthesis Market – Trends Forecast Till 2031

Market Snapshot

Market Overview

The global Peptide Synthesis Market size was estimated at USD 820 million in 2024 and is projected to reach USD 1,479.84 million in 2031 at a CAGR of 8.8 % during the forecast period 2025-2031.

The peptide synthesis market refers to the industry involved in the production and development of peptides, which are short chains of amino acids linked by peptide bonds. Peptides have a wide range of applications in pharmaceuticals, biotechnology, diagnostics, and cosmetics, playing a crucial role in drug discovery, diagnostics, and therapeutic treatments. The market includes the processes and technologies used for synthesizing peptides, such as solid-phase peptide synthesis (SPPS) and liquid-phase peptide synthesis, catering to both research and industrial-scale peptide production.

The scope of the peptide synthesis market is vast, encompassing various end-user segments, including pharmaceutical companies, research institutions, contract research organizations, and diagnostics labs. The market’s growth is driven by the increasing demand for peptide-based therapeutics, advancements in proteomics, and the rising focus on personalized medicine. Additionally, the growing popularity of biologics, such as peptide vaccines and hormone therapies, has expanded the need for efficient peptide synthesis technologies. The demand for high-quality synthetic peptides is also fueled by their applications in drug delivery systems, cancer therapies, and other therapeutic areas.

Current trends in the peptide synthesis market highlight significant technological advancements, including the development of automated synthesis platforms, improved resin and reagents, and advances in peptide sequence design. Automation in peptide synthesis has made the process faster, more reliable, and cost-effective. Moreover, the market is witnessing an increased focus on the production of long-chain peptides and complex peptide structures, which are required for the development of more sophisticated and targeted therapeutics. Innovations in peptide purification and characterization are also contributing to the growth of the market.

Several key drivers are contributing to the expansion of the peptide synthesis market, including the rising prevalence of chronic diseases such as cancer, diabetes, and cardiovascular diseases, which has led to a growing need for novel peptide-based treatments. The increasing investment in biotechnology research and the discovery of new peptides with therapeutic potential are also driving market growth. Moreover, the growing number of clinical trials focused on peptide-based therapies and the development of new methods for large-scale peptide production are expected to further boost the market in the coming years.

Delvens Industry Expert's Standpoint

Experts in the Peptide Synthesis Market highlight several key trends driving growth and innovation. The peptide synthesis market involves the production of peptides, which are used in pharmaceuticals, biotechnology, diagnostics, and cosmetics. It is driven by the growing demand for peptide-based therapeutics, advancements in proteomics, and personalized medicine. The market is expanding with technological innovations like automated synthesis platforms and improvements in peptide design, purification, and characterization. Key drivers include the increasing prevalence of chronic diseases, investment in biotechnology research, and the development of novel peptide-based treatments. The rise of biologics and peptide vaccines, along with advancements in large-scale peptide production, are expected to further fuel market growth.

Market Portfolio

Key Findings

• The products segment was the leading force in the peptide synthesis market in recent years. The market is categorized into products and services, with the products market further divided into consumables and instruments. Among these, consumables held the dominant position in the peptide synthesis market. Consumables are subdivided into reagents and other consumables, with the reagents market being further split into resins, amino acids, coupling reagents, dyes & fluorescent labeling reagents, deprotection agents, cleavage reagents, and others. The demand for advanced resins has increased due to heightened investments in pharmaceutical research and development and large-scale peptide-based therapeutic production. Additionally, innovations in resin technologies, such as preloaded resins and specialized linkers, have positively impacted peptide synthesis, facilitating the creation of more complex peptides. Examples include polystyrene-based resins for traditional SPPS and PEG-based resins for enhanced solubility and versatility.

• Peptide synthesizers led the instrument segment in recent years. The instrument segment includes peptide synthesizers, chromatography equipment, lyophilizers, and others, with peptide synthesizers taking the lead and expected to experience significant growth in the coming years. This growth is driven by technological advancements like improved automation, real-time monitoring, and AI integration for process optimization. Additionally, the introduction of advanced products is likely to further contribute to market expansion. For example, in May 2024, Activotec Ltd launched the Activo-Darwin Semi-Automated Peptide Synthesizer, designed for synthesizing high-quality peptides.

• Peptide synthesis services dominated the market in recent years. The services segment is divided into peptide library synthesis, peptide synthesis, peptide purification, and peptide analysis services. Peptide synthesis services took the lead, driven by the increasing demand for custom and complex peptides in drug discovery, therapeutics, and research. The growth is further supported by key players offering specialized services, including modifications and large-scale production at competitive prices. Peptide library synthesis services, an essential segment for drug discovery, biomarker identification, and therapeutic development, play a key role in driving this market forward.

• The chemical technique segment is expected to experience faster growth in the coming years. The market is segmented into chemical and biological techniques, with the chemical segment including solid-phase peptide synthesis (SPPS), solution-phase peptide synthesis, and others, while the biological segment covers recombinant DNA technology and enzymes. The chemical segment held the largest market share in recent years, with SPPS being the dominant technique due to its efficiency, scalability, and ability to produce high-purity peptides. Recombinant DNA (rDNA) technology also plays a significant role in peptide synthesis, particularly for producing complex peptides and proteins that are challenging to achieve using traditional chemical methods. rDNA-based peptide synthesis is beneficial for producing large-scale quantities of peptides and proteins with natural or post-translational modifications, essential for therapeutic applications.

• The cancer application segment is anticipated to grow rapidly in the future. The market is categorized into therapeutics, diagnostics, and research & development, with therapeutics further divided by indications such as cancer, diabetes, obesity, autoimmune diseases, and other conditions. The cancer segment is expanding rapidly, driven by the rising prevalence of cancer and the increasing use of peptide-based therapies, including targeted treatments, vaccines, and immunotherapies. The growth of peptide-based drugs for cancer is a major driver of this trend.

• Pharmaceutical and biotechnology companies held the largest share in the end-user segment in recent years. The market is divided into pharmaceutical and biotechnology companies, CDMOs & CROS, academic and research institutes, medical device companies, and hospitals & diagnostic centers. Pharmaceutical and biotechnology companies dominated the segment, driven by investments in targeted therapies and peptide-based drugs. The CDMO & CRO segment is expected to experience significant growth due to increased outsourcing of peptide synthesis and collaborations with biopharma companies for peptide-based product development. Additionally, expansions in manufacturing capabilities are expected to further drive market growth. For example, in January 2025, BioDuro, a Contract Research, Development, and Manufacturing Organization (CRDMO), opened a fully automated solid-phase peptide synthesis scale-up laboratory at the Shanghai Zhangjiang High-tech Park campus in China.

• The market is also divided into various regions such as North America, Europe, Asia-Pacific, South America, and Middle East and Africa. North America region is projected to hold the largest market share. Factors such as increasing demand for biopharmaceuticals, advancements in drug discovery, rising chronic disease prevalence, expanded R&D activities, and growing interest in personalized medicine and targeted therapeutics have triggered the Peptide Synthesis Market in the region.

Regional Analysis

North America to Dominate the Market

• North America leads the global peptide synthesis market due to its advanced pharmaceutical sector, cutting-edge technology, favorable regulations, and strong focus on the biopharmaceutical industry. The U.S. dominates the North American peptide synthesis market. Market growth is driven by the increasing prevalence of chronic diseases such as diabetes and obesity, boosting the demand for peptide-based therapeutics. Additionally, investments in research and development for personalized medicines and advanced synthesis technologies are significantly contributing to the market's expansion.
• The peptide synthesis market in Europe is expected to grow steadily. The biopharmaceutical industry, research institutes, and government support for scientific advancements have been key drivers. The approval of BiP-peptide programs by organizations such as the FDA has played an important role in promoting the market for peptide-based drugs across the region. The UK market is anticipated to see rapid growth, driven by significant investments in R&D, the rise in chronic diseases, and the presence of a robust biochemical industry. Additional factors such as urbanization, improved healthcare infrastructure, and diversification within the manufacturing sector are further fueling this growth. Germany holds a notable share of the peptide synthesis market, supported by its well-established pharmaceutical industry, extensive research, and production capabilities. The country is home to many large-scale pharmaceutical companies specializing in peptides, making it a leader in peptide synthesis globally.

Competitive Landscape

• Thermo Fisher Scientific, Inc.
• Merck KGaA
• Kaneka Corporation
• Agilent Technologies Inc.
• GenScript Biotech Corporation
• Bachem Holding AG

Recent Developments

• In May 2024, Vapourtec introduced the compact and versatile Peptide-ExplorerLT peptide synthesizer.
• In May 2024, Activotec Ltd unveiled the Activo-Darwin Semi-Automated Peptide Synthesizer, a device specifically engineered for the synthesis of high-quality peptides.

Reasons to Acquire

• Increase your understanding of the market for identifying the most suitable strategies and decisions based on sales or revenue fluctuations in terms of volume and value, distribution chain analysis, market trends, and factors.
• Gain authentic and granular data access for the Peptide Synthesis Market to understand the trends and the factors involved in changing market situations.
• Qualitative and quantitative data utilization to discover arrays of future growth from the market trends of leaders to market visionaries and then recognize the significant areas to compete in the future.
• In-depth analysis of the changing trends of the market by visualizing the historic and forecast year growth patterns.

Report Scope